NEW ARYLHEXAHYDROPYRIMIDINEDIONES - SYNTHESIS, BENZODIAZEPINE RECEPTOR AFFINITY AND ANTICONVULSANT ACTIVITY

Authors
GUILLON J DAOUST M RADULOVIC D BOULOUARD M DALLEMAGNE P LEGRAND E RAULT S QUERMONNE MA ROBBA M
Citation
J. Guillon et al., NEW ARYLHEXAHYDROPYRIMIDINEDIONES - SYNTHESIS, BENZODIAZEPINE RECEPTOR AFFINITY AND ANTICONVULSANT ACTIVITY, European journal of medicinal chemistry, 31(4), 1996, pp. 335-339
Citations number
10
Categorie Soggetti
Chemistry Medicinal
Journal title
European journal of medicinal chemistry → ACNP
ISSN journal
02235234
Volume
31
Issue
4
Year of publication
1996
Pages
335 - 339
Database
ISI
SICI code
0223-5234(1996)31:4<335:NA-SBR>2.0.ZU;2-0
Abstract
Synthesis of new 3-alkyl-6-arylhexahydropyrimidine-2,4-dione derivativ es was achieved starting from various benzaldehydes. Their affinity to wards the benzodiazepine receptor and their anticonvulsant effect were evaluated.