OPTIMIZATION OF THE SEPARATION OF THE DIMETHYLPYRIDINES BY CAPILLARY ELECTROPHORESIS

Authors
MCKILLOP AG SMITH RM ROWE RC WREN SAC
Citation
Ag. Mckillop et al., OPTIMIZATION OF THE SEPARATION OF THE DIMETHYLPYRIDINES BY CAPILLARY ELECTROPHORESIS, Journal of chromatography, 730(1-2), 1996, pp. 321-328
Citations number
11
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of chromatography → ACNP
Volume
730
Issue
1-2
Year of publication
1996
Pages
321 - 328
Database
ISI
SICI code
Abstract
The separation of the isomers of dimethylpyridine has been studied by capillary electrophoresis. Studies at low pH where the dimethylpyridin es all bear the same charge showed a partial separation probably due t o size/shape effects. The charge profiles of the analytes calculated f rom their ionisation constants were compared with their separation bet ween pH 2.5 and 9. The optimum resolution was found at a pH of 6.5 in the area of maximum charge difference between the dimethylpyridines.