HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF FLAVONOIDS FROM SIDERITIS SPECIES

The determination of flavonoids in the genus Sideritis (Lamiaceae) is described by a new reversed-phase highperformance liquid chromatograph y method. The ethyl acetate extract content of sixteen species of the genus Sideritis in isoscutelarein-7-O-[allosyl (1 --> 2) glucoside], l uteoline, hypolaetin-8-O-beta-D-glucoside, chrysoeriol, apigenine, sid erito-flavone, xantomicrol, gardenin D, 8-methoxy-cirsilineol and desm etilnobiletine is reported for the first time. Knowledge of the flavon oid content allows their relationship to the pharmacological potency t o be established and contributes to the botanical determination of the se species.