STEREOSELECTIVE SYNTHESIS OF L-[1-C-13], L-[2-C-13] AND L-[N-15] AMINO-ACIDS

Citation
A. Martin et al., STEREOSELECTIVE SYNTHESIS OF L-[1-C-13], L-[2-C-13] AND L-[N-15] AMINO-ACIDS, Isotopes in environmental and health studies, 32(1), 1996, pp. 15-19
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear","Environmental Sciences
ISSN journal
10256016
Volume
32
Issue
1
Year of publication
1996
Pages
15 - 19
Database
ISI
SICI code
1025-6016(1996)32:1<15:SSOLLA>2.0.ZU;2-5
Abstract
The precursor N-(diphenylmethylene) glycinyl camphor sultam has been s pecifically labelled by nitrogen-15 or carbon-13 starting from either NH4Cl, (K2CO3)-C-13 or (CH3NH2)-C-13 or labelled glycine. Akylation of these different labelled precursors by corresponding electrophiles yi elded the following labelled amino acids: Leu, Phe, Ala, Val, Ser, Asn , Gin, Asp, Trp and Cys.