RHENIUM(V) GLUCONATE, A SUITABLE PRECURSOR FOR THE PREPARATION OF RHENIUM(V) COMPLEXES

Authors
NOLL B KNIESS T FRIEBE M SPIES H JOHANNSEN B
Citation
B. Noll et al., RHENIUM(V) GLUCONATE, A SUITABLE PRECURSOR FOR THE PREPARATION OF RHENIUM(V) COMPLEXES, Isotopes in environmental and health studies, 32(1), 1996, pp. 21-29
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear","Environmental Sciences
Journal title
Isotopes in environmental and health studies → ACNP
ISSN journal
10256016
Volume
32
Issue
1
Year of publication
1996
Pages
21 - 29
Database
ISI
SICI code
1025-6016(1996)32:1<21:RGASPF>2.0.ZU;2-H
Abstract
Reduction of perrhenate with stannous chloride at an excess of sodium gluconate in aqueous solution results in formation of rhenium(V) gluco nate. The reaction proceeds slowly compared to that of pertechnetate. Aqueous solutions of rhenium(V) gluconate can be prepared down to a co ncentration level of at least 10(-4) mol . l(-1) within two hours. The usefulness of rhenium(V) gluconate to serve as a precursor for prepar ation of oxorhenium(V) complexes as potential radiotherapeutic agents is revealed by subsequent ligand exchange reactions carried out with m ercaptoacetyldiglycine, 3-thiapentane-dithiol-1,5/butanethiol and with 2-aminobenzenethiol.