CHEMOENZYMATIC SYNTHESIS OF (-(4E,15E)-DOCOSA-4,15-DIEN-1-YN-3-OL, A COMPONENT OF THE MARINE SPONGE CRIBROCHALINA-VASCULUM())

Authors
OHTANI T KIKUCHI K KAMEZAWA M HAMATANI H TACHIBANA H TOTANI T NAOSHIMA Y
Citation
T. Ohtani et al., CHEMOENZYMATIC SYNTHESIS OF (-(4E,15E)-DOCOSA-4,15-DIEN-1-YN-3-OL, A COMPONENT OF THE MARINE SPONGE CRIBROCHALINA-VASCULUM()), Journal of the Chemical Society. Perkin transactions. I, (10), 1996, pp. 961-962
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
10
Year of publication
1996
Pages
961 - 962
Database
ISI
SICI code
0300-922X(1996):10<961:CSO(AC>2.0.ZU;2-3
Abstract
An acetylenic alcohol, (+)-(4E, 15E)-docosa-4, 15-dien-1-yn-3-ol 1, is olated from the marine sponge Cribrochalina vasculum, was synthesized in highly enantiomerically pure form by lipase-catalysed transesterifi cation with Novozym 435 (Candida antarctica).