AUTOMATION OF SELECTIVE ASSAYS FOR ONLINE BIOPROCESS MONITORING BY FLOW-INJECTION ANALYSIS

On-line analysis of one component in a complex media used for bioproce sses requires the application of selective tests such as enzyme assays . Because these assays are susceptible to interference by other medium components and have a limited detection range, automatic sample pretr eatment is a prerequisite. The progress made with automatic sample pre treatment in flow-injection analysis makes this technique particularly suitable for on-line monitoring of bioprocesses. Moreover, newly deve loped software control systems may improve the necessary robustness of flow-injection analysis systems.