U. Mocek et al., ISOLATION AND STRUCTURE ELUCIDATION OF 5 NEW ASTERRIQUINONES FROM ASPERGILLUS, HUMICOLA AND BOTRYOTRICHUM SPECIES, Journal of antibiotics, 49(9), 1996, pp. 854-859
Five new quinone pigments have been discovered from the fermentation b
roth of Aspergillus, Humicola and Botryotrichum species isolated from
different soil samples. These compounds inhibit serine proteases of th
e coagulation pathway. Their structures which differ in the identity a
nd position of a 5-carbon side chain on the indole moiety have been el
ucidated based on NMR and FAB-MS experiments.