INHIBITORS OF BACTERIAL SIGNAL PEPTIDASE - A SERIES OF 6-(SUBSTITUTEDOXYETHYL)PENEMS

Authors
ALLSOP A BROOKS G EDWARDS PD KAURA AC SOUTHGATE R
Citation
A. Allsop et al., INHIBITORS OF BACTERIAL SIGNAL PEPTIDASE - A SERIES OF 6-(SUBSTITUTEDOXYETHYL)PENEMS, Journal of antibiotics, 49(9), 1996, pp. 921-928
Citations number
10
Categorie Soggetti
Pharmacology & Pharmacy",Immunology,"Biothechnology & Applied Migrobiology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
49
Issue
9
Year of publication
1996
Pages
921 - 928
Database
ISI
SICI code
0021-8820(1996)49:9<921:IOBSP->2.0.ZU;2-A
Abstract
A series of 6-(substituted oxyethyl)penem esters having the (5S) stere ochemistry which are potent inhibitors of Escherichia coli leader pept idase is described. Structure-activity relationships are discussed.