STEREO SELECTIVE SYNTHESIS OF 2-AMINO-1-HYDROXY-3-PHENYLPROPYLPHOSPHONIC ACID

Authors
ZYGMUNT J GANCARZ R LEJCZAK B WIECZOREK P KAFARSKI P
Citation
J. Zygmunt et al., STEREO SELECTIVE SYNTHESIS OF 2-AMINO-1-HYDROXY-3-PHENYLPROPYLPHOSPHONIC ACID, Bioorganic & medicinal chemistry letters, 6(24), 1996, pp. 2989-2992
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
24
Year of publication
1996
Pages
2989 - 2992
Database
ISI
SICI code
0960-894X(1996)6:24<2989:SSSO2>2.0.ZU;2-L
Abstract
A highly stereoselective synthesis of 2-amino-1-hydroxy-3-phenylpropyl -phosphonic acid was achieved by simple addition of diethyl phosphite to enantiomeric N-blocked phenylalaninals. These compouds exhibit sign ificant herbicidal activity. Copyright (C) 1996 Elsevier Science Ltd