L. Giorno et al., DOWNSTREAM PROCESSING OF LACTIC-ACID BY MEMBRANE-BASED SOLVENT-EXTRACTION, Separation science and technology, 31(16), 1996, pp. 2159-2169
Lactic acid has extensive use in the food and chemical industry, About
half the lactic acid used in the world is produced by fermentation of
carbohydrates using lactic acid bacteria. The recovery of lactic acid
from the fermentation broth is more difficult than the fermentation i
tself. In the present work a study of membrane-based solvent extractio
n as a separation unit for the continuous downstream processing of lac
tic acid from fermentation broth was carried out. The experiments were
performed using simulated fermentation broths made of lactic acid in
acetate buffer or distilled water as the feed solution. The effects of
membrane material, organic carrier, and pH of the feed solution on me
mbrane extraction efficiency were investigated. A separation degree of
35% was obtained by using a polyetheretherketone (PEEK-WC 14%) membra
ne with 5% trioctylamine as the organic carrier in n-heptane. The expe
rimental results obtained with the simulated system encourage the use
of membrane-based solvent extraction with a real fermentation broth.