C. Roy et al., VALUE OF THE CRITERION OF ASYMMETRY FOR T HE DIAGNOSIS OF SMALL PELVIC LYMPH-NODE IN MRI (INFERIOR OR EQUAL TO 1 CM), Journal de radiologie, 77(12), 1996, pp. 1183-1187
The purpose of this study was to determine if lymph node asymmetry in
small (<1.0 cm) pelvic nodes was a significant prognostic feature in d
etermining metastatic disease. 216 patients who presented pelvic carci
noma underwent MR Imaging. They were correlated to pathological findin
gs obtained by surgery. We considered on the axial plan the maximum di
ameter (MAD) of both round or oval-shaped suspicious masses. Two diffe
rent cut-off values were determined : node diameter superior to 1.0 cm
(criterion 1) and node diameter superior to 0.5 cm with asymmetry rel
ative to the opposite side for nodes ranging from 0.5 cm to 1.0 cm (cr
iterion 2). With criterion 1 MR Imaging had an accuracy of 88%, a sens
itivity of 65%, a specificity of 96%, a PPV of 88% and a NPV of 88% in
detection of pelvic node metastasis. By considering criterion 2, MR I
maging had an accuracy of 85%, a sensitivity of 75%, a specificity of
89%, a PPV of 71% and a NPV of 91%. Normal small asymmetric lymph node
s were present in 5.6% of cases. Asymmetry of normal or inflammatory p
elvic nodes is not uncommon. It cannot be relied on to diagnose metast
atic involvement in cases of small suspicious lymph nodes, especially
because of its low specificity and positive predictive value.