COMPARATIVE ACTIVITY OF AZITHROMYCIN AGAINST CLINICAL ISOLATES OF MYCOBACTERIA

Authors
WATT B RAYNER A HARRIS G
Citation
B. Watt et al., COMPARATIVE ACTIVITY OF AZITHROMYCIN AGAINST CLINICAL ISOLATES OF MYCOBACTERIA, Journal of antimicrobial chemotherapy, 38(3), 1996, pp. 539-542
Citations number
11
Categorie Soggetti
Microbiology,"Pharmacology & Pharmacy","Infectious Diseases
Journal title
Journal of antimicrobial chemotherapy → ACNP
ISSN journal
03057453
Volume
38
Issue
3
Year of publication
1996
Pages
539 - 542
Database
ISI
SICI code
0305-7453(1996)38:3<539:CAOAAC>2.0.ZU;2-H
Abstract
Azithromycin exhibited in-vitro activity against 20 clinical isolates of Mycobacterium avium complex for which the MIC(90) was 32 mg/L and 2 2 clinical isolates of other mycobacteria but showed no activity again st 20 isolates of Mycobacterium tuberculosis (MIC(90) > 128 mg/L) nor against the single isolate of Mycobacterium marinum tested (MIC 128 mg /L). These results suggest that the drug may prove useful for the prop hylaxis and treatment of infections due to non-tuberculous mycobacteri a, including M. avium complex in patients with AIDS.