RENAL-CELL CARCINOMA AFTER THERAPY FOR NEUROBLASTOMA

OBJECTIVE. An unfortunate consequence of increased success in childhoo d cancer survival rates is the increase in the number of secondary mal ignant neoplasms after therapy for the initial lesion. Renal cell carc inoma can occur as a secondary malignant neoplasm after therapy for ne uroblastoma and may become more common as more patients with treated n euroblastomas survive into adulthood. We studied one case and reviewed four cases of secondary renal cell carcinoma to determine if the rela tionship between these two neoplasms is significant. CONCLUSION. An aw areness of the association between these two neoplasms is important in the diagnostic follow-up of neuroblastoma so that secondary renal cel l carcinoma is not confused with recurrence of primary disease.