EXTRAMEDULLARY PLASMACYTOMA DIAGNOSED BY FINE-NEEDLE ASPIRATION CYTOLOGY - A REPORT OF 4 CASES

BACKGROUND: Fine needle aspiration cytology (FNAC) diagnosis of plasma cytoma is rare. CASES: Four cases of plasmacytoma were diagnosed by FN AC. The patients had clinically palpable lesions in more than one anat omic site. The sites of aspiration included lymph nodes, soft tissue s wellings and a bony mass. The ages of the patients ranged from 42 to 8 0 years (mean, 62 years), and all the patients were male. All four cas es showed a monomorphous population of well-differentiated myeloma cel ls in aspiration smears. Serum electrophoresis demonstrated an M spike in all cases, and Bence Jones protein was detected in the urine sampl e in one case. Radiologic and bone marrow findings also substantiated the diagnosis of multiple myeloma. CONCLUSION: FNAC diagnosis of plasm acytoma at extramedullary sites offers the opportunity for noninvasive verification of widespread involvement.