Rr. Pai et Cv. Raghuveer, EXTRAMEDULLARY PLASMACYTOMA DIAGNOSED BY FINE-NEEDLE ASPIRATION CYTOLOGY - A REPORT OF 4 CASES, Acta cytologica, 40(5), 1996, pp. 963-966
BACKGROUND: Fine needle aspiration cytology (FNAC) diagnosis of plasma
cytoma is rare. CASES: Four cases of plasmacytoma were diagnosed by FN
AC. The patients had clinically palpable lesions in more than one anat
omic site. The sites of aspiration included lymph nodes, soft tissue s
wellings and a bony mass. The ages of the patients ranged from 42 to 8
0 years (mean, 62 years), and all the patients were male. All four cas
es showed a monomorphous population of well-differentiated myeloma cel
ls in aspiration smears. Serum electrophoresis demonstrated an M spike
in all cases, and Bence Jones protein was detected in the urine sampl
e in one case. Radiologic and bone marrow findings also substantiated
the diagnosis of multiple myeloma. CONCLUSION: FNAC diagnosis of plasm
acytoma at extramedullary sites offers the opportunity for noninvasive
verification of widespread involvement.