(+ AHYDRO-4A-METHYL-7,7-DIPHENYL-1(2H)-NAPHTHALENONE/

Authors
BUNCE RA CHILDRESS RS
Citation
Ra. Bunce et Rs. Childress, (+ AHYDRO-4A-METHYL-7,7-DIPHENYL-1(2H)-NAPHTHALENONE/, Synthetic communications, 26(21), 1996, pp. 4081-4089
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
26
Issue
21
Year of publication
1996
Pages
4081 - 4089
Database
ISI
SICI code
0039-7911(1996)26:21<4081:(A>2.0.ZU;2-9
Abstract
The title compound was prepared in 48% overall yield using a seven-ste p sequence. The synthesis involves stepwise construction of a 3-formyl -3,3-diphenylpropyl side chain from the double bond of 3-ethenyl-3-met hylcyclohexanone followed by aldol ring closure. The approach represen ts a general strategy for the synthesis of a number of iaryl-3,4,4a,5, 6,7-hexahydro-1(2H)-naphthalenones.