ALPHA-VINYLLYSINE AND ALPHA-VINYLARGININE ARE TIME-DEPENDENT INHIBITORS OF THEIR COGNATE DECARBOXYLASES

Authors
BERKOWITZ DB JAHNG WJ PEDERSEN ML
Citation
Db. Berkowitz et al., ALPHA-VINYLLYSINE AND ALPHA-VINYLARGININE ARE TIME-DEPENDENT INHIBITORS OF THEIR COGNATE DECARBOXYLASES, Bioorganic & medicinal chemistry letters, 6(18), 1996, pp. 2151-2156
Citations number
41
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
18
Year of publication
1996
Pages
2151 - 2156
Database
ISI
SICI code
0960-894X(1996)6:18<2151:AAAATI>2.0.ZU;2-8
Abstract
(+/-)-alpha-Vinyllysine and (+/-)-alpha-vinylarginine display time-dep endent inhibition of L-lysine decarboxylase from B. cadaveris, and L-a rginine decarboxylase from E. coli, respectively. A complete Kitz-Wils on analysis has been performed using a modification of the Palcic cont inuous UV assay for decarboxylase activity. Copyright (C) 1996 Elsevie r Science Ltd