B. Pfaffenbach et al., EFFECT OF LUMBAR ORTHESES WITH ABDOMINAL COMPRESSION ON GASTROESOPHAGEAL REFLUX AND GASTROINTESTINAL TRANSIT, Deutsche Medizinische Wochenschrift, 121(51-52), 1996, pp. 1592-1597
Objective: To investigate the effect of lumbar ortheses with abdominal
compression on gastro-oesophageal reflux and gastrointestinal transit
. Patients and methods: In a prospective study 20 consecutive patients
with lumbar syndrome treated with lumbar orthesis (10 female, 10 male
, median age 54.6 years) were investigated for gastro-oesophageal refl
ux, mouth-to-cecum transit time (MCT), and whole-gut transit time. Gas
tro-oesophageal reflux was assessed performing an ambulatory pH meteri
ng of the distal oesophagus over a period of 10 h with and without ort
heses on two separate study days. After positioning of the pH catheter
patients ingested a liquid-solid test meal labelled with 10 g lactulo
se and 750 g indigocarmine to determine MCT with the hydrogen breath t
est and whole-gut transit by the first appearance of indigocarmine in
the stool. Dyspepsia was assessed by using a standardized questionnair
e. Results: Lumbar ortheses induced a significant increase in reflux t
ime (pH < 4) (8.1 vs 4.1%), total number of reflux episodes (102.5 vs
69.5) and duration of longest reflux episode (6.0 vs 3.7 min) (P < 0.0
5). 12 patients with ortheses revealed an increase in relative reflux
time (2.1 - 24.5%, median: 8.2%) more than two standard deviations com
pared to previously obtained normal values. In these patients during o
rtheses dyspeptic symptoms correlated significantly with reflux time (
r = 0.6; P < 0.05). In contrast, MCT and whole-gut transit time in pat
ients with and without ortheses did not differ significantly (85 vs 85
min; 10.2 vs 9.6 h). Conclusion: Lumbar ortheses with abdominal compr
ession, nowadays frequently used in the lumbar syndrome, produce gastr
o-oesophageal reflux associated with dyspepsia. Gastrointestinal trans
it time is not affected, though.