ISOLATION AND APPLICATION OF CHROMOSOME-6 SPECIFIC MICROSATELLITE MARKERS FOR DETECTION OF QTL FOR MILK-PRODUCTION TRAITS IN CATTLE

Basic techniques for generation of chromosome fragment specific marker s providing a prerequisite for high resolution mapping were developed. QTL detection for milk production traits on bovine chromosome 6 was p erformed in five German HF half sib families according to a granddaugh ter design. Testing 11 informative chromosome 6 markers locus order wa s established. For each son and marker locus the inherited paternal al lele was determined and mean BVs for milk production traits of those s ons receiving the alternative paternal alleles were determined. Signif icant differences could be detected in 3 families. There is indication for at least two QTL with different effects in the vicinity, bur: pro bably not within the casein locus itself.