A prospective study was performed to determine whether multiple repeat
coronary angioplasty can achieve final lesion patency after restenosi
s, Between 1983 and 1992, 1455 lesions (excluding acute myocardial inf
arction or total occlusion) were successfully dilated for the first ti
me. Only 941 (68%) of the 1385 lesions followed up showed improved cor
onary flow (less than or equal to 70% stenosis) after the first proced
ure. However, 1248 (93%) of 1345 lesions showed improved coronary flow
after angioplasty had been repeated as many as three times, and 1268
(94%) of 1345 did so after as many as six procedures, Only 23 (1.6%) l
esions required four or more procedures, and 20 of them showed final p
atency, These findings indicate that repeat angioplasty can be used as
a reasonable treatment strategy for restenosis.