SOLID-PHASE SYNTHESIS OF ARYL AMINES

Authors
WILLOUGHBY CA CHAPMAN KT
Citation
Ca. Willoughby et Kt. Chapman, SOLID-PHASE SYNTHESIS OF ARYL AMINES, Tetrahedron letters, 37(40), 1996, pp. 7181-7184
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
40
Year of publication
1996
Pages
7181 - 7184
Database
ISI
SICI code
0040-4039(1996)37:40<7181:SSOAA>2.0.ZU;2-O
Abstract
A method for the solid phase synthesis of aryl amines is reported. The method involves a palladium mediated coupling reaction between aryl b romides and amines. The products are isolated in high purity and good yields. This method should prove to be a useful tool for constructing combinatorial libraries containing the aryl amine moiety. Copyright (C ) 1996 Elsevier Science Ltd