BIOACTIVE SAPONINS AND GLYCOSIDES .4. 4 METHYL-MIGRATED 16,17-SECO-DAMMARANE TRITERPENE GLYCOSIDES FROM CHINESE NATURAL MEDICINE, HOVENIAE-SEMEN-SEU-FRUCTUS, THE SEEDS AND FRUIT OF HOVENIA-DULCIS THUNB - ABSOLUTE STEREOSTRUCTURES AND INHIBITORY ACTIVITY ON HISTAMINE-RELEASE OF HOVENIDULCIOSIDES A(1), A(2), B-1, AND B-2

Authors
YOSHIKAWA M MURAKAMI T UEDA T MATSUDA H YAMAHARA J MURAKAMI N
Citation
M. Yoshikawa et al., BIOACTIVE SAPONINS AND GLYCOSIDES .4. 4 METHYL-MIGRATED 16,17-SECO-DAMMARANE TRITERPENE GLYCOSIDES FROM CHINESE NATURAL MEDICINE, HOVENIAE-SEMEN-SEU-FRUCTUS, THE SEEDS AND FRUIT OF HOVENIA-DULCIS THUNB - ABSOLUTE STEREOSTRUCTURES AND INHIBITORY ACTIVITY ON HISTAMINE-RELEASE OF HOVENIDULCIOSIDES A(1), A(2), B-1, AND B-2, Chemical and Pharmaceutical Bulletin, 44(9), 1996, pp. 1736-1743
Citations number
29
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
44
Issue
9
Year of publication
1996
Pages
1736 - 1743
Database
ISI
SICI code
0009-2363(1996)44:9<1736:BSAG.4>2.0.ZU;2-A
Abstract
Four bioactive methyl-migrated 16,17-seco-dammarane type triterpene gl ycosides called hovenidulciosides A(1), A(2), B-1, and B-2 were isolat ed from a Chinese natural medicine, Hoveniae Semen Seu Fructus, the se eds and fruit of Hovenia dulcis THUNB. (Rhamnaceae) together with hodu loside III and (+)-gallocatechin. The absolute stereostructures of hov enidulciosides A(1), A(2), B-1, and B-2 have been elucidated bu chemic al and physicochemical evidence. All were found to inhibit the histami ne release from rat peritoneal exudate cells induced by compound 48/80 and calcium ionophore A-23187.