INDUCTION OF HEAT-SHOCK PROTEIN-60 EXPRESSION IN HUMAN MONOCYTIC CELL-LINES INFECTED WITH MYCOBACTERIUM-LEPRAE

Authors
BEIMNET K SODERSTROM K JINDAL S GRONBERG A FROMMEL D KIESSLING R
Citation
K. Beimnet et al., INDUCTION OF HEAT-SHOCK PROTEIN-60 EXPRESSION IN HUMAN MONOCYTIC CELL-LINES INFECTED WITH MYCOBACTERIUM-LEPRAE, Infection and immunity, 64(10), 1996, pp. 4356-4358
Citations number
22
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
64
Issue
10
Year of publication
1996
Pages
4356 - 4358
Database
ISI
SICI code
0019-9567(1996)64:10<4356:IOHPEI>2.0.ZU;2-L
Abstract
Monocytic cell lines (HL-60 and THP-1) were infected with viable Mycob acterium leprae. Levels of human hsp60 were estimated by Western blot (immunoblot) assay and a sandwich enzyme-linked immunosorbent assay. T he results showed that infection of both of the cell lines induced the synthesis of human hsp60, which may be of significance in relation to autoimmune manifestations associated with mycobacterial infections.