PRIMARY ANETODERMA IN CHILDREN - REPORT OF 2 CASES AND LITERATURE-REVIEW

Two boys, age 7 and 9 years, with the diagnosis of primary anetoderma are presented. In one patient a growing number of indolent lesions dev eloped for one year on the neck. The other boy complained of single le sions appearing over four months on the arms, feet, and chest wall. In dividual lesions measured up to 1 cm in diameter and showed a palpable herniation phenomenon and wrinkled surface. The lesions did not have an inflammatory onset. Histologically, in both patients the diagnosis of anetoderma was verified by loss of elastic fibers and a lymphohisti ocytic infiltration in the middermis. Administration of oral penicilli n for three weeks did not result in marked improvement, and atrophic m acules continued to appear in the younger boy. Although no autoimmonol ogic abnormalities or other associated diseases have arisen in our pat ients, long-term follow-up is mandatory to detect autoimmune disorders that are reported to occur in the course of the disease.