THE SYNTHESIS OF FLUORINE-CONTAINING PTERINS

Authors
DUNN C GIBSON CL SUCKLING CJ
Citation
C. Dunn et al., THE SYNTHESIS OF FLUORINE-CONTAINING PTERINS, Tetrahedron, 52(40), 1996, pp. 13017-13026
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
40
Year of publication
1996
Pages
13017 - 13026
Database
ISI
SICI code
0040-4020(1996)52:40<13017:TSOFP>2.0.ZU;2-S
Abstract
The synthesis of some 7,7-difluoro-7,8-digydropterins and pterins with fluoroalkyl subsitutents at the 6 or 7 positions from fluorine-contai ning aliphatic precursors and suitably substituted pyrimidines is desc ribed. The fluorine-containing pterins were found to be very insoluble and also stable to nucleophiles and bases in dilute aqueous solution. Copyright (C) 1996 Elsevier Science Ltd