Background and Objectives. A 58-year-old man developed progressive neu
rologic symptoms following a surgical procedure and postoperative epid
ural analgesia. Methods. Neurologic evaluation, magnetic resonance ima
ging, computed tomography, and electromyography indicated the presence
of both arachnoiditis and Guillain-Barre syndrome. The patient was tr
eated with plasmapheresis and methylprednisone. Results. The patient b
egan to show clinical and electromyographic recovery but was lost to f
ollow-up after his transfer to a rehabilitation facility. Conclusions.
Anesthesiologists should be aware of the possible postoperative occur
rence of rare neurologic disorders, both in patients who have received
epidural analgesia and in those who have not, but they should not be
deterred from using epidural analgesia by this isolated case.