The number of thrombolytic drugs for the management of acute myocardia
l infarction is rapidly expanding. New agents, some of which are bioch
emically modified versions of currently available thrombolytics, will
soon arrive in the marketplace. The pharmacologic differences of the n
ew drugs are the basis for clinical differences such as enhanced clot
lysis and prolonged elimination half-life. Ultimately, these features
may result in improved infarct artery patency and patient survival.