A 26-year old female developed acute fulminant amoebic colitis during
the post-partum period, successfully managed by subtotal colonic resec
tion without anastomosis. Fulminant transmural amoebic colitis is a ra
re life-threatening complication of invasive bowel amebiasis. Pregnanc
y, delivery, diabetes mellitus and immunodeficiency are the main risk
factors. At pathologic examination, bowel wall necrosis can be seen wi
th amoebae present in the lumen of capillary vessels. The diagnosis of
amoebic colonic perforation is difficult, especially in a non-endemic
area. Conservative surgical management is required in non-perforated
forms. If perforated, the bowel must be resected, limited to macroscop
ic lesions.