Hepatoblastoma in, adults is a rare malignancy that presents in the ep
ithelial or mixed epithelial-mesenchymal variants. We report two cases
, the former representing the epithelial and the latter the mixed type
. A 21 year-old woman with epigastric pain had abdominal ultrasound an
d CT scans showing a large hepatic mass; A right trisegmentectomy was
performed. The first and second recurrences were treated by resection.
The third recurrence was treated by hepatic transarterial chemo-embol
ization, systemic chemotherapy and 19 percutaneous alcohol injections.
A careful follow up by abdominal ultrasound and CT scans was able to
detect the recurrence at an early stage. The patient is well at 151 mo
nths. A 39 year-old man with epigastric pain, and dyspepsia had upper-
GI series and abdominal CT scan, showing a left hepatic mass involving
the stomach. Liver resection and Billroth II hemigastrectomy were per
formed. A recurrence involving the Left hepatic lobe, the spleen and t
he remaining stomach occurred 15 months later and the patient died fro
m multi organ. failure. Surgery is the treatment of choice of hepatobl
astoma in, adults. Recurrences can also be treated aggressively by sur
gical resections if no extrahepatic organs are involved. Other therape
utic modalities can be attempted whenever surgery is not possible.