MINIMAL EFFECT OF CNTF ON THE ULTRASTRUCTURE OF AXOTOMISED MOTONEURONS IN THE ADULT-RAT

Authors
DEMETRIOU T DUBERLEY RM JOHNSON IP
Citation
T. Demetriou et al., MINIMAL EFFECT OF CNTF ON THE ULTRASTRUCTURE OF AXOTOMISED MOTONEURONS IN THE ADULT-RAT, Brain research, 733(2), 1996, pp. 312-317
Citations number
30
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
733
Issue
2
Year of publication
1996
Pages
312 - 317
Database
ISI
SICI code
0006-8993(1996)733:2<312:MEOCOT>2.0.ZU;2-W
Abstract
The ultrastructural effects of CNTF or BSA on the retrograde response of adult rat spinal motoneurones were quantified at 7 days. Axotomy wi th or without CNTF or BSA generally resulted in fragmentation of the r ough endoplasmic reticulum (RER). One third of CNTF-treated motoneuron es had RER with a more ordered lamella arrangement than controls. Decr eased area of the Golgi apparatus was seen after CNTF and BSA treatmen t. Other features of the retrograde response were unaffected.