OCCURRENCE OF MYELOMA IN A CHRONIC LYMPHOCYTIC-LEUKEMIA PATIENT AFTERRESPONSE TO DIFFERENTIATION THERAPY WITH INTERLEUKIN-4

Authors
MAKOWER D VENKATRAJ U DUTCHER JP WIERNIK PH
Citation
D. Makower et al., OCCURRENCE OF MYELOMA IN A CHRONIC LYMPHOCYTIC-LEUKEMIA PATIENT AFTERRESPONSE TO DIFFERENTIATION THERAPY WITH INTERLEUKIN-4, Leukemia & lymphoma, 23(5-6), 1996, pp. 617-619
Citations number
11
Categorie Soggetti
Hematology
Journal title
Leukemia & lymphoma → ACNP
ISSN journal
10428194
Volume
23
Issue
5-6
Year of publication
1996
Pages
617 - 619
Database
ISI
SICI code
1042-8194(1996)23:5-6<617:OOMIAC>2.0.ZU;2-P
Abstract
The occurrence of chronic lymphocytic leukemia (CLL) and multiple myel oma (MM) in a single individual is rare, and the clonal relationship b etween the two neoplasms is unclear. We describe here a patient with C LL who developed symptoms of MM while responding to experimental thera py with interleukin-4 (IL-4). This patient was treated with 2-chlorode oxyadenosine (2-CDA), and had a response in both malignancies.