As the recipient list for patients requiring lung transplantation cont
inues to increase, cadaveric donor lung availability has remained stat
ic. Our experience with utilizing lobes from living related donors for
bilateral pulmonary transplantation in 20 patients has yielded a 75%
survival at 1 year follow-up. Morbidity and mortality have been predom
inately due to infection. Rejection episodes have been mild and unilat
eral and have responded to augmented corticosteroids. Pulmonary functi
on tests in the recipients tend to improve steadily during the first y
ear postoperatively, and the patients have excellent functional capaci
ty. There have been no significant complications in the donors. On the
basis of our clinical experience, we have found that bilateral lobar
transplantation utilizing living related donors has resulted in organ
availability that can be lifesaving in critically in patients and can
provide a good alternative in certain noncritical, deteriorating patie
nts.