To isolate genes differentially expressed in the rat brain cortex and
cerebellum, a subtractive cDNA cloning procedure requiring only small
quantities of poly(A(+)) RNA, followed by differential screening, was
used. Two novel genes, MK and 3L7, with cortex- and cerebellum-specifi
c expression were identified. These genes displayed different expressi
on patterns in the brain cortex, cerebellum, and hippocampus during po
stnatal development.