POSITIVE-ION ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY OF OLIGONUCLEOTIDES

Authors
SANNESLOWERY KA MACK DP HU PF MEI HY LOO JA
Citation
Ka. Sanneslowery et al., POSITIVE-ION ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY OF OLIGONUCLEOTIDES, Journal of the American Society for Mass Spectrometry, 8(1), 1997, pp. 90-95
Citations number
32
Categorie Soggetti
Chemistry Physical","Chemistry Analytical",Spectroscopy
Journal title
Journal of the American Society for Mass Spectrometry → ACNP
ISSN journal
10440305
Volume
8
Issue
1
Year of publication
1997
Pages
90 - 95
Database
ISI
SICI code
1044-0305(1997)8:1<90:PEMOO>2.0.ZU;2-3
Abstract
Positive ion electrospray ionization mass spectra have been obtained o f deoxyribonucleic acids (DNA) and ribonucleic acids (RNA), including transfer RNAs (77-mer, similar to 25 kDa). For several different solut ion conditions, the charge state distributions of DNA and RNA molecule s were determined. It is postulated that the production of the multipl y charged positive ions results from gas phase dissociation of complex es between nitrogen-containing bases and oligonucleotides. (C) 1997 Am erican Society for Mass Spectrometry