MICRODIALYSIS SYSTEM FOR CONTINUOUS GLUCOSE MONITORING

A microdialysis system for continuous glucose monitoring has been deve loped. The system has been optimized for in vivo applications. All the components have been miniaturized to get a small wearable device. It consists of a small gas driven syringe pump, a microdialysis sampling stage, a specially developed silicon flow-through sensor chip and the electronics. Integrated on the sensor chip are the glucose sensor elem ents together with a system of capillaries and flow channels. Each pro cess step of the chip fabrication has been designed as a full wafer pr ocess to achieve mass-production compatibility The total system perfor mance is demonstrated by in vitro measurements taken from human serum and glucose standard solutions.