S. Langard et al., FATAL ACCIDENT RESULTING FROM METHYL-BROMIDE POISONING AFTER FUMIGATION OF A NEIGHBORING HOUSE - LEAKAGE THROUGH SEWAGE PIPES, Journal of applied toxicology, 16(5), 1996, pp. 445-448
An intoxication after using methyl bromide (CH3Br) in fumigation is re
ported. The accident resulted in the death of a newborn infant within
12-13 h after exposure, as well as clinical intoxication of the infant
's parents. The concentration of bromide ion in the infant's blood was
170 mg l(-1) and in the parents blood it was 130 and 110 mg l(-1). Au
topsy showed that the cause of death was acute pneumonia due to aspira
tion, most likely resulting from vomiting and aspiration after inhalat
ion of CH3Br. The clinical symptoms of the parents are reported, as we
ll as a brief survey on the kinetics and CH3Br toxicity in animals and
humans. Reconstruction of the events prior to the intoxication reveal
ed that the sewage pipes serving the two houses had been sucked empty
only 1-2 h prior to the start of fumigation, resulting in an open sewa
ge connection between the houses and permitting CH3Br to leak from the
treated house into the house of the affected family.