To assess the current picture of vitamin D deficiency, we reviewed all
17 cases of vitamin D-deficiency rickets seen in the referral clinic
of a children's hospital in Toronto between 1988 adn 1993. The diagnos
is was made at 7 to 33 months of age. All the children were symptomati
c: all had biochemical and radiographic abnormalities, two suffered hy
pocalcemic seizures, and all had bowing of the extremities. Twelve of
the children were born to parents who were recent immigrants to Canada
. All were of Asian or African origin with dark skin. All the children
had been exclusively breastfed with no vitamin D supplementation, and
had had little or no sun-light exposure. All the patients responded t
o vitamin D therapy. We conclude that vitamin D-deficiency rickets rem
ains an environmental/nutritional deficiency disease in this city and
that efforts at prevention should target children with pigmented skin
from families who are recent immigrants.