FIBRIN GLUE APPLICATION IN CONJUNCTION WITH TETRACYCLINE ROOT CONDITIONING AND CORONALLY POSITIONED FLAP PROCEDURE IN THE TREATMENT OF HUMAN GINGIVAL RECESSION DEFECTS

A split-mouth clinical study was designed to determine the effect of f ibrin glue (FG) in addition to tetracycline HCl (TTC) root conditionin g and the coronally positioned flap (CPF) procedure in the treatment o f maxillary buccal recession defects. 11 patients presenting with a pa ir of Class I or II recession defects were selected. After initial the rapy, defect-specific and full-mouth oral hygiene standards and gingiv al condition, recession depth, recession width, probing depth, attachm ent level, and width of keratinized gingiva were recorded. The surgica l procedure included elevation of a full split thickness flap, root de bridement and root conditioning with a 10 mg/ml TTC solution for 4 min utes. According to a randomization list, in each patient, I defect was treated with topical FG application, while the paired defect did not receive FG. The flap was adapted and sutured coronally to the cemento- enamel junction without tension. Healing was evaluated 6 months postsu rgery. Significant recession depth reduction and attachment gain were observed for both treatments. Average root coverage amounted to 65% in FG treated defects and 55% in defects treated with TTC conditioning o nly. There were no clinical and statistical significant differences be tween the treatments for any parameter considered. This study suggests that FG may not meaningfully enhance the outcome of the CPF procedure with TTC root conditioning.