ADMINISTRATION OF FISH-OIL BY GAVAGE INCREASES THE ACTIVITIES OF HEXOKINASE, GLUCOSE-6-PHOSPHATE-DEHYDROGENASE, AND CITRATE SYNTHASE IN RATLYMPHOID ORGANS

1. The effect of administration of fish oil by gavage on key enzyme ac tivities of glucose metabolism of the thymus, spleen, and mesenteric l ymph nodes was investigated. 2. The activities of hexokinase, glucose- 6-phosphate dehydrogenase, and citrate synthase in the lymphoid organs were markedly raised due to a daily administration of fish oil by gav age (0.4% of body weight). 3. These findings indicate that the therape utic utilization of fish oil does affect the metabolism of the lymphoi d organs, and possibly immune function; however, the mechanism involve d remains to be investigated.