M. Joao et al., SYNTHESIS OF CARBAMATE-PROTECTED SPERMIDINE HOMOLOGS THROUGH ALKANE-ALPHA,OMEGA-DIAMINES, Journal of chemical research. Synopses, (8), 1996, pp. 366-367
The total synthesis of three triamines selectively protected in the pr
imary amino groups [BocNH(CH2)(n)NHCH(2)CH(2)CH(2)NHZ, n = 3-5] (1a-c)
and two triamines protected in the secondary amino function and in on
e of the primary amino functions [EtOCONH(CH2)(n)N(Boc)CH2CH2CH2NH2, n
=3 and 5] (2a and 2c), based on a simple and efficient procedure, is d
escribed.