EFFICACY OF 101 ANTIMICROBIALS AND OTHER AGENTS ON THE DEVELOPMENT OFCRYPTOSPORIDIUM-PARVUM IN-VITRO

Authors
WOODS KM NESTERENKO MV UPTON SJ
Citation
Km. Woods et al., EFFICACY OF 101 ANTIMICROBIALS AND OTHER AGENTS ON THE DEVELOPMENT OFCRYPTOSPORIDIUM-PARVUM IN-VITRO, Annals of tropical medicine and parasitology, 90(6), 1996, pp. 603-615
Citations number
64
Categorie Soggetti
Tropical Medicine",Parasitiology
Journal title
Annals of tropical medicine and parasitology → ACNP
ISSN journal
00034983
Volume
90
Issue
6
Year of publication
1996
Pages
603 - 615
Database
ISI
SICI code
0003-4983(1996)90:6<603:EO1AAO>2.0.ZU;2-8
Abstract
An in-situ ELISA was used as a primary screen to test the effects of 1 01 antimicrobials and other agents on the development of Cryptosporidi um parvum in vitro. Over 40 of the compounds displayed some form of an ticryptosporidial activity, and dose-response curves were generated fo r 40 of these. The in-situ ELISA makes a highly effective primary, pha rmaceutical screen for C. parvum, to be used Drier to more detailed mi croscopical, toxicological or in-vivo assays.