CHARACTERIZATION OF CLINICAL ISOLATES OF BETA-LACTAMASE-NEGATIVE, HIGHLY AMPICILLIN-RESISTANT ENTEROCOCCUS-FAECALIS

Authors
CERCENADO E VICENTE MF DIAZ MD SANCHEZCARRILLO C SANCHEZRUBIALES M
Citation
E. Cercenado et al., CHARACTERIZATION OF CLINICAL ISOLATES OF BETA-LACTAMASE-NEGATIVE, HIGHLY AMPICILLIN-RESISTANT ENTEROCOCCUS-FAECALIS, Antimicrobial agents and chemotherapy, 40(10), 1996, pp. 2420-2422
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
40
Issue
10
Year of publication
1996
Pages
2420 - 2422
Database
ISI
SICI code
0066-4804(1996)40:10<2420:COCIOB>2.0.ZU;2-K
Abstract
We analyzed the penicillin-binding protein (PBP) profiles of two clini cal isolates of Enterococcus faecalis for which ampicillin MICs were 3 2 and 64 mu g/ml. Six PBPs were detected in both isolates, demonstrati ng an apparently increased amount of PBP 5 and decreased penicillin bi nding of PBPs 1 and 6. These results suggest that ampicillin resistanc e in the clinical isolates of E. faecalis described could be associate d with alterations in different PBPs.