PALMAR FASCIITIS AND POLYARTHRITIS ASSOCIATED WITH OVARIAN-CARCINOMA IN A YOUNG PATIENT A CASE-REPORT AND REVIEW OF THE LITERATURE

Palmar fasciitis and polyarthritis (PFPA) is an uncommon syndrome char acterized by progressive and extensive rheumatic disease. It has usual ly been associated with neoplasms, most commonly in elderly patients, preceding or accompanying the diagnosis of malignancy, We report a cas e of a 25-year-old patient with severe deforming PFPA preceding the di agnosis of carcinoma of the ovary, The histopathological findings of d iffuse fibrosis, connective tissue proliferation and vasculitis with C 3 and IgM deposits in subcutaneous tissue and synovia may further clar ify the possible pathogenesis of this unique syndrome.