INFLAMMATORY OPACITIES OF THE VITREOUS IN RIFABUTIN-ASSOCIATED UVEITIS

PURPOSE: To describe rifabutin-associated uveitis with opacities in th e inferior and posterior vitreous in three patients with acquired immu nodeficiency syndrome. METHOD: Case reports of the three patients are presented. RESULTS: The patients, who were being treated with rifabuti n and fluconazole, developed anterior and posterior uveitis. The poste rior uveitis was characterized by white yellow inflammatory opacities located in the inferior and posterior vitreous. Discontinuation of rif abutin and the start of topical corticosteroid therapy resulted in imp rovement of the uveitis and visual acuity. CONCLUSION: Recognition of rifabutin-associated uveitis with opacities in the inferior and poster ior vitreous may prevent unnecessary invasive diagnostic and therapeut ic procedures.