BILATERAL PAPILLEDEMA WITH RETINAL HEMORRHAGES IN ASSOCIATION WITH CEREBRAL VENOUS SINUS THROMBOSIS AND PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA

PURPOSE: To report a patient with paroxysmal nocturnal hemoglobinuria who complained of transient obscurations of vision and exhibited bilat eral papilledema with retinal hemorrhages. METHODS: Case report Comput ed tomography did not demonstrate any abnormality but magnetic resonan ce imaging disclosed signs of cerebral venous sinus thrombosis. RESULT S: The patient was treated with subcutaneous low molecular weight hepa rin and intravenous corticosteroids. Symptoms improved within one week and ophthalmoscopic signs resolved within four months. CONCLUSION: Bi lateral papilledema with extensive retinal hemorrhages may be a sign o f cerebral venous sinus thrombosis, a reported devastating complicatio n of paroxysmal nocturnal hemoglobinuria. Thus, any patient with suspe cted cerebral venous sinus thrombosis should undergo magnetic resonanc e imaging, even when results of computed tomography are normal.