This paper examines the problem of founding irreversibility on reversi
ble equations of motion from the point of view of the Brussels school'
s recent developments in the foundations of quantum statistical mechan
ics. A detailed critique of both their 'subdynamics' and 'transformati
on' theory is given. It is argued that the subdynamics approach involv
es a generalized form of 'coarse-graining' description, whereas, trans
formation theory cannot lead to truly irreversible processes pointing
to a preferred direction of time. It is concluded that the Brussels sc
hool's conception of microscopic temporal irreversibility, as such, is
tacitly assumed at the macroscopic level. Finally a logical argument
is provided which shows, independently of the mathematical formalism o
f the theory concerned, that statistical reasoning alone is not suffic
ient to explain the arrow of time.