LOGRANK, PLAY THE WINNER, POWER AND ETHICS

Authors
HALLSTROM A BROOKS MM PECKOVA M
Citation
A. Hallstrom et al., LOGRANK, PLAY THE WINNER, POWER AND ETHICS, Statistics in medicine, 15(20), 1996, pp. 2135-2142
Citations number
3
Categorie Soggetti
Statistic & Probability","Medicine, Research & Experimental","Public, Environmental & Occupation Heath","Statistic & Probability","Medical Informatics
Journal title
Statistics in medicine → ACNP
ISSN journal
02776715
Volume
15
Issue
20
Year of publication
1996
Pages
2135 - 2142
Database
ISI
SICI code
0277-6715(1996)15:20<2135:LPTWPA>2.0.ZU;2-4
Abstract
We show by simulation and numerical integration techniques that power is largely unaffected by play the winner strategies in a typical chron ic disease mortality trial utilizing the logrank test. This raises the issue of the ethics of equal allocation in such a setting.