THE B MACROPHAGE CELL - AN ELUSIVE LINK BETWEEN CD5(+) B-LYMPHOCYTES AND MACROPHAGES/

Authors
BORRELLO MA PHIPPS RP
Citation
Ma. Borrello et Rp. Phipps, THE B MACROPHAGE CELL - AN ELUSIVE LINK BETWEEN CD5(+) B-LYMPHOCYTES AND MACROPHAGES/, Immunology today, 17(10), 1996, pp. 471-475
Citations number
36
Categorie Soggetti
Immunology
Journal title
Immunology today → ACNP
ISSN journal
01675699
Volume
17
Issue
10
Year of publication
1996
Pages
471 - 475
Database
ISI
SICI code
0167-5699(1996)17:10<471:TBMC-A>2.0.ZU;2-V
Abstract
For decades, immunologists have reported conversion of B-lymphocytic t umors to cells with properties of macrophages. This process was consid ered to be an anomalous result of malignancy in mice and in humans. Fo r patients, the consequences of this biphenotypic cancer are a poor pr ognosis and low remission rate. Here, Melinda Borrello and Richard Phi pps discuss the identification of a normal counterpart to these malign ant B/macrophage cells.