S. Oshima et al., MOTHER TO FRY, SUCCESSFUL TRANSFER OF IMMUNITY AGAINST INFECTIOUS HEMATOPOIETIC NECROSIS VIRUS-INFECTION IN RAINBOW-TROUT, Journal of General Virology, 77, 1996, pp. 2441-2445
We have tested whether immunity can be transferred from a mother fish
to its fry. Rainbow trout mother fish were inoculated against infectio
us haematopoietic necrosis virus (IHNV) by intraperitoneal injection o
f a fragment of the IHNV glycoprotein spanning amino acids 31 to 310.
This protein fragment was obtained by isolating the specific cDNA from
Japanese IHNV strain HV7601 and expressing it in Escherichia coli. Fr
y from immunized and control fish were exposed to IHNV at various inte
rvals after hatching, and their mortality monitored. Survival of the f
ry of immunized fish was significantly greater when exposure to virus
occurred 7 days after hatching, and some immunity appeared to persist
until at least 25 days after hatching.