SOLID-PHASE EXTRACTION OF 2,4-D FROM HUMAN URINE

A method for determining urinary concentrations of 2,4-D in samples co llected from non-occupationally, environmentally exposed individuals w as developed. The 2,4-D was extracted from fortified human urine sampl es using octadecylsilane solid phase extraction cartridges. The averag e percent recovery for urine samples spiked at 2 and 20 ng/mL was 100% and 93%, respectively. The method detection limit was estimated to be 0.75 ng of 2,4-D per mL of urine based on a 10 mL sample size. The po tential use of 2,4-dichlorophenylacetic acid as a surrogate standard w as also investigated. Copyright (C) 1996 Elsevier Science Ltd.